Invention Grant
US09539238B2 Pharmaceutical composition comprising a biguanide derivative as an active ingredient for preventing or treating glioblastoma
有权
包含双胍衍生物作为预防或治疗胶质母细胞瘤的活性成分的药物组合物
- Patent Title: Pharmaceutical composition comprising a biguanide derivative as an active ingredient for preventing or treating glioblastoma
- Patent Title (中): 包含双胍衍生物作为预防或治疗胶质母细胞瘤的活性成分的药物组合物
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Application No.: US15154788Application Date: 2016-05-13
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Publication No.: US09539238B2Publication Date: 2017-01-10
- Inventor: Seok Gu Kang , Ji Hyun Lee , Jong Hee Chang , Jae Ho Cheong , Jun Jeong Choi , Sung Wuk Kim , Sang Hee Yoo , Hong Woo Kim , Soon Im Lee
- Applicant: ImmunoMet Therapeutics, Inc.
- Applicant Address: US TX Houston
- Assignee: IMMUNOMET THERAPEUTICS, INC
- Current Assignee: IMMUNOMET THERAPEUTICS, INC
- Current Assignee Address: US TX Houston
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Priority: KR10-2015-0066845 20150513
- Main IPC: A01N43/52
- IPC: A01N43/52 ; A61K31/40 ; A61K31/495
Abstract:
The present invention provides novel uses of a biguanide derivative for preventing or treating glioblastoma. The compound of Formula 1 and its pharmaceutically acceptable salts can be used for preventing and treating glioblastoma. Further, the combined treatment of the compound of Formula 1 and temozolomide can provide superior effects compared to the administration of the compound of Formula 1 alone or temozolomide alone.
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