Invention Grant
- Patent Title: Combination of immunotherapies with activators of Tie-2
- Patent Title (中): 免疫治疗与Tie-2激活剂的组合
-
Application No.: US14819871Application Date: 2015-08-06
-
Publication No.: US09539245B2Publication Date: 2017-01-10
- Inventor: Kevin Peters
- Applicant: Aerpio Therapeutics, Inc.
- Applicant Address: US OH Cincinnati
- Assignee: AERPIO THERAPEUTICS, INC.
- Current Assignee: AERPIO THERAPEUTICS, INC.
- Current Assignee Address: US OH Cincinnati
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07D277/30 ; A61K31/427 ; A61K38/45 ; A61K39/395 ; A61K31/00
Abstract:
The present invention relates to combination therapies comprising at least one activator of Tie-2 and immunotherapies that target immune checkpoints. Combination therapies of the disclosure can provide therapeutic effects not obtained with singly-administered immunotherapies. Combination therapies can be used to increase the therapeutic efficacy of an immunotherapy, to provide lower dosages of an immunotherapy being administered, to lower a toxicity of an immunotherapy, or to manage a side effect of an immunotherapy.
Public/Granted literature
- US20160038467A1 Combination of Immunotherapies with Activators of Tie-2 Public/Granted day:2016-02-11
Information query
