Invention Grant
US09539256B2 Modulators of exchange proteins directly activated by cAMP (EPACS)
有权
由cAMP（EPACS）直接激活的交换蛋白的调节剂
- Patent Title: Modulators of exchange proteins directly activated by cAMP (EPACS)
- Patent Title (中): 由cAMP（EPACS）直接激活的交换蛋白的调节剂
-
Application No.: US14377574Application Date: 2013-02-08
-
Publication No.: US09539256B2Publication Date: 2017-01-10
- Inventor: Xiaodong Cheng , Jia Zhou , Tamara Tsalkova , Fang Mei , Haijun Chen
- Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Agency: Norton Rose Fulbright US LLP
- International Application: PCT/US2013/025319 WO 20130208
- International Announcement: WO2013/119931 WO 20130815
- Main IPC: A61K31/513
- IPC: A61K31/513 ; A61K31/42 ; A61K31/4709 ; A61K45/06 ; A61K31/136 ; A61K31/10 ; A61K31/277 ; A61K31/505
Abstract:
Embodiments of the invention are directed to compounds that inhibit an activity of EP AC proteins and methods of using the same. The inventors have developed a sensitive and robust high throughput screening (HTS) assay for the purpose of identifying EPAC specific inhibitors (Tsalkova et al. (2012) PLOS ONE 7(1):e30441).
Public/Granted literature
- US20150110809A1 MODULATORS OF EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP (EPACS) Public/Granted day:2015-04-23
Information query
IPC分类:
