Invention Grant
- Patent Title: Cyclophosphamide in combination with immune therapeutics
- Patent Title (中): 环磷酰胺联合免疫治疗
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Application No.: US13232326Application Date: 2011-09-14
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Publication No.: US09539267B2Publication Date: 2017-01-10
- Inventor: Robert A. Brodsky , Richard J. Jones , Richard F. Ambinder
- Applicant: Robert A. Brodsky , Richard J. Jones , Richard F. Ambinder
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University
- Current Assignee: The Johns Hopkins University
- Current Assignee Address: US MD Baltimore
- Agency: Foley Hoag LLP
- Main IPC: A01N43/00
- IPC: A01N43/00 ; A61K31/33 ; A61K31/664 ; A61K39/395
Abstract:
The present invention relates to methods of treating a cancer and in particular, a B-cell derived cancer, using a lymphocytotoxic but hematopoeitic cell sparing high-dose pulsed amount of an oxazaphosphorine drug, either alone, or in combination with immune therapeutics such as, for example, monoclonal antibodies that selectively bind B-cell specific antigens.
Public/Granted literature
- US20120100162A1 Cyclophosphamide in Combination with Immune Therapeutics Public/Granted day:2012-04-26
Information query
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