A system is disclosed for preparing a hypodermic injection site comprising a visibility enhancer for an injection site and a post injection hypodermic puncture wound site. The present invention offers a number of significant improvements which advance the efficacy of the art, by: preventing unintentional hypodermic injection of medicines through un-sanitized or under-sanitized skin surfaces, thereby protecting patients from becoming inoculated with pathogenic microorganisms while receiving such injections; significantly improving the visibility of, and, the accurate visual location and bandaging of post-injection needle puncture entry wounds, thereby further reducing the risk of infection of such wounds; and, by reducing bleeding from such wounds, which, in turn, reduces healthcare worker exposure to blood-borne pathogens and reduces the generation of potentially infectious, biohazardous medical waste.