Invention Grant
US09539328B2 Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
有权
防篡改组合物包含氢可酮和对乙酰氨基酚，用于快速发作和延长的止痛持续时间
- Patent Title: Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
- Patent Title (中): 防篡改组合物包含氢可酮和对乙酰氨基酚，用于快速发作和延长的止痛持续时间
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Application No.: US14479129Application Date: 2014-09-05
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Publication No.: US09539328B2Publication Date: 2017-01-10
- Inventor: Krishna Devarakonda , Michael J. Giuliani , Vishal K. Gupta , Ralph A. Heasley , Susan Shelby
- Applicant: MALLINCKRODT LLC
- Applicant Address: US MO Hazelwood
- Assignee: MALLINCKRODT LLC
- Current Assignee: MALLINCKRODT LLC
- Current Assignee Address: US MO Hazelwood
- Agency: Mayer Brown LLP
- Main IPC: A61K9/20
- IPC: A61K9/20 ; A61K47/10 ; A61K51/12 ; A61K9/24 ; A61K31/167 ; A61K31/485
Abstract:
The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof.
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