Invention Grant
US09539334B2 Orally dissolving thin films containing allergens and methods of making and use
有权
口服溶解含有过敏原的薄膜和制造和使用方法
- Patent Title: Orally dissolving thin films containing allergens and methods of making and use
- Patent Title (中): 口服溶解含有过敏原的薄膜和制造和使用方法
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Application No.: US14400856Application Date: 2013-05-17
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Publication No.: US09539334B2Publication Date: 2017-01-10
- Inventor: Robert Wood , Hai-Quan Mao , Corinne Keet , Russell Martin
- Applicant: THE JOHNS HOPKINS UNIVERSITY
- Applicant Address: US MD Baltimore
- Assignee: John Hopkins University
- Current Assignee: John Hopkins University
- Current Assignee Address: US MD Baltimore
- Agency: John Hopkins Technology Transfer
- International Application: PCT/US2013/041552 WO 20130517
- International Announcement: WO2013/173697 WO 20131121
- Main IPC: A61K39/35
- IPC: A61K39/35 ; A61K47/38 ; A61K45/06 ; A61K47/10 ; A61K9/00 ; A61K9/70 ; A61K47/26 ; B29C39/02 ; A61K47/32 ; B29L7/00
Abstract:
The present invention provides a thin mucoadhesive sublingual film composition which provides improved allergen delivery and efficacy at a smaller dose while prolonging the contact time between the allergen and oral antigen presenting cells (APCs), and therefore minimizing the risk of systemic side effects. The thin film compositions of the present invention are also easier to standardize, and removes any need for measuring allergen doses at the physician's office, and which allows for a simplified dosing schedule. Methods of making the thin film compositions and methods for their use are also disclosed.
Public/Granted literature
- US20150125495A1 ORALLY DISSOLVING THIN FILMS CONTAINING ALLERGENS AND METHODS OF MAKING AND USE Public/Granted day:2015-05-07
Information query
