Invention Grant
- Patent Title: Method to improve the tumor diagnostic efficiency of multivalent ligands by regulating the stoichiometric ratio between inner surface functionalities and ligand moieties for tumor targeting
- Patent Title (中): 通过调节肿瘤靶向的内表面功能和配体部分之间的化学计量比来改善多价配体的肿瘤诊断效率的方法
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Application No.: US14254365Application Date: 2014-04-16
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Publication No.: US09539345B2Publication Date: 2017-01-10
- Inventor: Yoonkyung Kim , Ju Young Heo , June-key Chung , Young-Hwa Kim , Seok Ki Kim , Se Hun Kang
- Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , NATIONAL CANCER CENTER
- Applicant Address: KR Daejeon KR Goyang-Si
- Assignee: Korea Research Institute of Bioscience and Biotechnology,National Cancer Center
- Current Assignee: Korea Research Institute of Bioscience and Biotechnology,National Cancer Center
- Current Assignee Address: KR Daejeon KR Goyang-Si
- Agency: Lathrop & Gage LLP
- Priority: KR10-2014-0033724 20140321
- Main IPC: A61K51/08
- IPC: A61K51/08 ; A61K49/00 ; A61K51/06

Abstract:
Disclosed herein is a method of improving tumor diagnostic efficiency of multivalent ligands by regulating the stoichiometric ratio between inner surface functionalities and ligand moieties for tumor targeting, and the multivalent ligands for tumor diagnosis.
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