Invention Grant
US09540321B2 Process for large scale production of 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole dimesylate monohydrate
有权
大规模生产1 - [（2-溴苯基）磺酰基] -5-甲氧基-3 - [（4-甲基-1-哌嗪基）甲基] -1H-吲哚二甲酸一水合物
![Process for large scale production of 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole dimesylate monohydrate](/docs/US/2017-01-10/US09540321B2/abs.jpg.600x600.jpg)
- Patent Title: Process for large scale production of 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole dimesylate monohydrate
- Patent Title (中): 大规模生产1 - [（2-溴苯基）磺酰基] -5-甲氧基-3 - [（4-甲基-1-哌嗪基）甲基] -1H-吲哚二甲酸一水合物
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Application No.: US15100489Application Date: 2014-02-20
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Publication No.: US09540321B2Publication Date: 2017-01-10
- Inventor: Ramakrishna Nirogi , Rama Sastri Kambhampati , Anil Karbhari Shinde , Venkateswarlu Jasti
- Applicant: SUVEN LIFE SCIENCES LIMITED
- Applicant Address: IN Hyderbad
- Assignee: SUVEN LIFE SCIENCES LIMITED
- Current Assignee: SUVEN LIFE SCIENCES LIMITED
- Current Assignee Address: IN Hyderbad
- Agency: IPHorgan LTD.
- Priority: IN5537/CHE/2013 20131202
- International Application: PCT/IN2014/000109 WO 20140220
- International Announcement: WO2015/083179 WO 20150611
- Main IPC: C07D209/14
- IPC: C07D209/14
![Process for large scale production of 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole dimesylate monohydrate](/abs-image/US/2017/01/10/US09540321B2/abs.jpg.150x150.jpg)
Abstract:
A process suitable for adoption to large scale manufacture of 1-[(2-bromophenyl-sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole dimesylate monohydrate, which is a selective 5-HT6 receptor antagonist intended for the symptomatic treatment of Alzheimer's disease and other disorders of memory and cognition like Attention deficient hyperactivity, Parkinson's and Schizophrenia.
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