Invention Grant
US09540332B2 Benzimidazole derivatives as selective blockers of persistent sodium current
有权
苯并咪唑衍生物作为持续钠电流的选择性阻断剂
- Patent Title: Benzimidazole derivatives as selective blockers of persistent sodium current
- Patent Title (中): 苯并咪唑衍生物作为持续钠电流的选择性阻断剂
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Application No.: US14494734Application Date: 2014-09-24
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Publication No.: US09540332B2Publication Date: 2017-01-10
- Inventor: George R. Ehring , Ellen Chao , Herman Ng , Hau Ton , Jia Chian Li , Joseph S. Adorante , Michael E. Garst , Howard B. Rind , Mark R. Hansen , Alfred Arthur Avey, Jr. , Lloyd Jay Dolby , Shervin Esfandiari , Vivian R. MacKenzie , Jeremiah Andrew Marsden , David Charles Muchmore
- Applicant: Allergan, Inc.
- Applicant Address: US CA Irvine
- Assignee: ALLERGAN, INC.
- Current Assignee: ALLERGAN, INC.
- Current Assignee Address: US CA Irvine
- Agent Jonathan Bass
- Main IPC: C07D235/12
- IPC: C07D235/12 ; C07D235/06 ; C07D403/06 ; C07D401/12 ; C07D235/14 ; C07D235/08 ; C07D403/12 ; C07D235/20
Abstract:
The present invention is directed to a compound of Formula I or a pharmaceutically acceptable salt thereof; wherein R, R1, R2, R3, R4, m, and n are as defined herein, to pharmaceutical compositions comprising said compound, and to methods of treating diseases or conditions mediated by elevated persistent sodium current, such as an ocular disorder, multiple sclerosis, seizure disorder, and chronic pain.
Public/Granted literature
- US20160355485A9 BENZIMIDAZOLE DERIVATIVES AS SELECTIVE BLOCKERS OF PERSISTENT SODIUM CURRENT Public/Granted day:2016-12-08
Information query
