Invention Grant
- Patent Title: Diamide inhibitors of cytochrome P450
- Patent Title (中): 细胞色素P450的二酰胺抑制剂
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Application No.: US14565039Application Date: 2014-12-09
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Publication No.: US09540354B2Publication Date: 2017-01-10
- Inventor: Michael Eissenstat , Dehui Duan
- Applicant: SEQUOIA PHARMACEUTICALS, INC.
- Applicant Address: US MD Potomac
- Assignee: SEQUOIA PHARMACEUTICALS, INC.
- Current Assignee: SEQUOIA PHARMACEUTICALS, INC.
- Current Assignee Address: US MD Potomac
- Agency: Perkins Coie LLP
- Main IPC: C07D307/91
- IPC: C07D307/91 ; C07D405/14 ; C07D231/12 ; C07D307/79 ; C07D405/06 ; C07D405/12 ; C07D409/12 ; C07D417/12 ; C07D417/14 ; A61K31/343 ; A61K31/4155 ; A61K31/443 ; A61K45/06 ; C07D307/81
Abstract:
Methods of inhibiting cytochrome P450 enzymes are provided that can be used for improving the treatment of diseases by preventing degradation of drugs or other molecules by cytochrome P450. Pharmaceutical compositions are provided that can act as boosters to improve the pharmacokinetics, enhance the bioavailability, and enhance the therapeutic effect of drugs that undergo in vivo degradation by cytochrome P450 enzymes.
Public/Granted literature
- US20150087676A1 Diamide Inhibitors of Cytochrome P450 Public/Granted day:2015-03-26
Information query
