Invention Grant
US09540362B2 Sphingosine-1-phosphate receptor agonists, methods of preparing the same, and pharmaceutical compositions containing the same as an active agent
有权
鞘氨醇-1-磷酸受体激动剂，其制备方法以及含有它们作为活性剂的药物组合物
- Patent Title: Sphingosine-1-phosphate receptor agonists, methods of preparing the same, and pharmaceutical compositions containing the same as an active agent
- Patent Title (中): 鞘氨醇-1-磷酸受体激动剂，其制备方法以及含有它们作为活性剂的药物组合物
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Application No.: US14764116Application Date: 2014-02-19
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Publication No.: US09540362B2Publication Date: 2017-01-10
- Inventor: Seung Yup Paek , Sung Bae Lee , Deok Seong Park , Won Hyung Lee
- Applicant: LG LIFE SCIENCES LTD.
- Applicant Address: KR Seoul
- Assignee: LG LIFE SCIENCES LTD.
- Current Assignee: LG LIFE SCIENCES LTD.
- Current Assignee Address: KR Seoul
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: KR10-2013-0018293 20130220
- International Application: PCT/KR2014/001336 WO 20140219
- International Announcement: WO2014/129796 WO 20140828
- Main IPC: C07D271/12
- IPC: C07D271/12 ; C07D413/04 ; A61K31/4245 ; C07D413/14 ; C07D403/12 ; C07D231/56 ; C07D401/12 ; C07D471/04 ; C07D209/08 ; C07D209/30
Abstract:
The present invention relates to novel compounds of Formula 1 as sphingosine-1-phosphate receptor agonists which can be effectively used for the treatment of autoimmune diseases, a method for preparing the same, and a pharmaceutical composition comprising the same as an active component. The compounds according to the present invention are effective on extensive autoimmune diseases and chronic inflammatory diseases including relapsing-remitting multiple sclerosis, and can also be used for treating or preventing immunoregulation disorders.
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