Invention Grant
- Patent Title: Solid oral formulations and crystalline forms of an inhibitor of apoptosis protein
- Patent Title (中): 固体口服制剂和结晶形式的凋亡蛋白抑制剂
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Application No.: US14095313Application Date: 2013-12-03
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Publication No.: US09540363B2Publication Date: 2017-01-10
- Inventor: Jeewan Thakur , Dong Yang , Lili Feng
- Applicant: Dong Yang , Lili Feng
- Applicant Address: CH
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH
- Agent Jennifer Chapman
- Main IPC: C07D417/04
- IPC: C07D417/04 ; A61K9/00 ; A61K38/00 ; A61K9/20 ; A61K31/427
Abstract:
The present disclosure relates to crystalline form of (S)—N—((S)-1-cyclohexyl-2-{(S)-2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide, salts and hydrates thereof. This disclosure also relates to solid oral formulation of (S)—N—((S)-1-cyclohexyl-2-{(S)-2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide, pharmaceutically acceptable salts, solvates (including hydrates) thereof, as well as methods of treatment using the same.
Public/Granted literature
- US20140093570A1 Solid Oral Formulations and Crystalline Forms of an Inhibitor of Apoptosis Protein Public/Granted day:2014-04-03
Information query
