Invention Grant
US09540368B2 1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins
有权
1H-吡咯并[2,3-c]吡啶-7（6H） - 酮和吡唑并[3,4-c]吡啶-7（6H） - 酮作为BET蛋白质的抑制剂
![1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins](/docs/US/2017-01-10/US09540368B2/abs.jpg.600x600.jpg)
- Patent Title: 1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins
- Patent Title (中): 1H-吡咯并[2,3-c]吡啶-7（6H） - 酮和吡唑并[3,4-c]吡啶-7（6H） - 酮作为BET蛋白质的抑制剂
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Application No.: US14693424Application Date: 2015-04-22
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Publication No.: US09540368B2Publication Date: 2017-01-10
- Inventor: Andrew P. Combs , Thomas P. Maduskuie, Jr.
- Applicant: Incyte Corporation
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: C07D471/04
- IPC: C07D471/04
![1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins](/abs-image/US/2017/01/10/US09540368B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to substituted pyrrolopyridinones and substituted pyrazolopyridinones which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer.
Public/Granted literature
- US20150307493A1 1H-PYRROLO[2,3-c]PYRIDIN-7(6H)-ONES AND PYRAZOLO[3,4-c]PYRIDIN-7(6H)-ONES AS INHIBITORS OF BET PROTEINS Public/Granted day:2015-10-29
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