Invention Grant
US09540369B2 Use of kinase inhibitors to increase the susceptibility of gram positive bacteria to beta lactam antibiotics
有权
使用激酶抑制剂增加革兰氏阳性细菌对β-内酰胺类抗生素的敏感性
- Patent Title: Use of kinase inhibitors to increase the susceptibility of gram positive bacteria to beta lactam antibiotics
- Patent Title (中): 使用激酶抑制剂增加革兰氏阳性细菌对β-内酰胺类抗生素的敏感性
-
Application No.: US14695813Application Date: 2015-04-24
-
Publication No.: US09540369B2Publication Date: 2017-01-10
- Inventor: Robert Todd Striker , John-Demian Sauer , Nathan Wlodarchak
- Applicant: Wisconsin Alumni Research Foundation
- Applicant Address: US WI Madison
- Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
- Current Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
- Current Assignee Address: US WI Madison
- Agency: Boyle Fredrickson, S.C.
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/437 ; C07D471/04 ; C07D487/04
Abstract:
Methods of using certain kinase inhibitors for treating Gram positive bacterial infections are disclosed. When co-administered with a β-lactam antibiotic, the disclosed compounds increase the susceptibility of infectious Gram positive bacteria to the β-lactam antibiotic.The disclosed kinase inhibitors have either of the general formulas: or the specific formula:
Public/Granted literature
Information query
