Invention Grant
- Patent Title: Host cell lines expressing recombinant GDF-5 protein
- Patent Title (中): 表达重组GDF-5蛋白的宿主细胞系
-
Application No.: US14610590Application Date: 2015-01-30
-
Publication No.: US09540429B2Publication Date: 2017-01-10
- Inventor: David S. Scher , Roger E. Harrington
- Applicant: WARSAW ORTHOPDEDIC, INC.
- Applicant Address: US IN Warsaw
- Assignee: Warsaw Orthopedic, Inc.
- Current Assignee: Warsaw Orthopedic, Inc.
- Current Assignee Address: US IN Warsaw
- Agency: Sorell Lenna & Schmidt LLP
- Main IPC: C12N1/21
- IPC: C12N1/21 ; C12N15/16 ; C12N15/63 ; C12N15/70 ; C12N15/71 ; C12N15/72 ; C07K14/51 ; C07K14/475 ; C07K1/14 ; C07K1/36
Abstract:
Expression vector systems are provided for increased production of a recombinant GDF-5 (rhGDF-5) protein. Also provided are transformed host cells that were engineered to produce and express high levels of rhGDF-5 protein. Methods for production and high expression of rhGDF-5 protein are disclosed herein. The methods of enhancing production and protein expression of rhGDF-5 protein as disclosed are cost-effective, time-saving and are of manufacturing quality.
Public/Granted literature
- US20150252088A1 METHODS AND COMPOSITIONS COMPRISING HUMAN RECOMBINANT GROWTH AND DIFFERENTIATION FACTOR-5 (RHGDF-5) Public/Granted day:2015-09-10
Information query
IPC分类:
