Invention Grant
- Patent Title: Human antibodies and antibody-drug conjugates against CD74
- Patent Title (中): 针对CD74的人抗体和抗体 - 药物偶联物
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Application No.: US13982959Application Date: 2012-02-01
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Publication No.: US09540433B2Publication Date: 2017-01-10
- Inventor: Sandra Verploegen , Marije Overdijk , Riemke Van Dijkhuizen , Willem Karel Bleeker , Patrick Van Berkel , Paul Parren , Steen Lisby
- Applicant: Sandra Verploegen , Marije Overdijk , Riemke Van Dijkhuizen , Willem Karel Bleeker , Patrick Van Berkel , Paul Parren , Steen Lisby
- Applicant Address: DK Copenhagen
- Assignee: GENMAB A/S
- Current Assignee: GENMAB A/S
- Current Assignee Address: DK Copenhagen
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- Priority: DK201100064 20110201
- International Application: PCT/EP2012/051679 WO 20120201
- International Announcement: WO2012/104344 WO 20120809
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/30 ; C07K16/42 ; C07K16/18 ; A61K47/48 ; A61K51/10 ; A61K31/7088 ; A61K35/17 ; A61K35/76 ; A61K38/16 ; A61K38/19 ; A61K45/06 ; A61K39/00

Abstract:
Isolated human monoclonal antibodies which bind to human CD74 and related antibody-drug conjugates are disclosed. Pharmaceutical compositions comprising the antibodies or antibody-drug conjugates, and therapeutic and diagnostic methods for using the antibodies and/or antibody-drug conjugates, are also disclosed.
Public/Granted literature
- US20140030273A1 HUMAN ANTIBODIES AND ANTIBODY-DRUG CONJUGATES AGAINST CD74 Public/Granted day:2014-01-30
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