Invention Grant
- Patent Title: Vector comprising multiple homologous nucleotide sequences
- Patent Title (中): 包含多个同源核苷酸序列的载体
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Application No.: US14641669Application Date: 2015-03-09
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Publication No.: US09540660B2Publication Date: 2017-01-10
- Inventor: Robin Steigerwald
- Applicant: BAVARIAN NORDIC A/S
- Applicant Address: DK Kvistgaard
- Assignee: BAVARIAN NORDIC A/S
- Current Assignee: BAVARIAN NORDIC A/S
- Current Assignee Address: DK Kvistgaard
- Main IPC: C12N15/86
- IPC: C12N15/86
Abstract:
The invention relates to vectors comprising two or more homologous nucleotide sequences and methods for generating them. The invention concerns substituting bases in the homologous nucleotide sequences with different bases that do not alter the encoded amino acid sequence. The invention allows for the reduction of intramolecular recombination between homologous nucleotide sequences, in particular in mammalian cells. The invention further relates to nucleotide sequences containing substituted bases.
Public/Granted literature
- US20160017369A1 VECTOR COMPRISING MULTIPLE HOMOLOGOUS NUCLEOTIDE SEQUENCES Public/Granted day:2016-01-21
Information query
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