Invention Grant
- Patent Title: PCA3 genes
- Patent Title (中): PCA3基因
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Application No.: US14033699Application Date: 2013-09-23
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Publication No.: US09540696B2Publication Date: 2017-01-10
- Inventor: Marion J. G. Bussemakers , William B. Isaacs
- Applicant: Stichting Katholieke Universiteit, more particularly The University Medical Centre Nijmegen
- Applicant Address: NL Nijmegen US MD Baltimore
- Assignee: Stichting Katholieke Universiteit, The University Medical Centre Nijmegen,The Johns Hopkins University
- Current Assignee: Stichting Katholieke Universiteit, The University Medical Centre Nijmegen,The Johns Hopkins University
- Current Assignee Address: NL Nijmegen US MD Baltimore
- Agency: McNeill Baur PLLC
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12Q1/68 ; C07K14/47 ; A61K38/00
Abstract:
The present invention relates, in general, to a prostate-specific antigen, PCA3. In particular, the present invention relates to nucleic acid molecules coding for the PCA3 protein; purified PCA3 proteins and polypeptides; recombinant nucleic acid molecules; cells containing the recombinant nucleic acid molecules; antibodies having binding affinity specifically to PCA3 proteins and polypeptides; hybridomas containing the antibodies; nucleic acid probes for the detection of nucleic acids encoding PCA3 proteins; a method of detecting nucleic acids encoding PCA3 proteins or polypeptides in a sample; kits containing nucleic acid probes or antibodies; bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess, or prognose a mammal afflicted with prostate cancer; therapeutic uses; and methods of preventing prostate cancer in an animal.
Public/Granted literature
- US20140017774A1 PCA3, PCA3 GENES, AND METHODS OF USE Public/Granted day:2014-01-16
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