A method and terminal are described for allocating resources for transmitting a signal in a multiple-input multiple-output (MIMO) wireless communication system. An uplink signal is transmitted using L layers at a terminal in a multiple-input multiple-output (MIMO) wireless communication system. Modulation symbols are generated by modulating output bit sequences of an interleaver matrix by a unit of log2 Q bits, where Q is a modulation order. Each of the output bit sequences has a size of L·log2 Q bits. The modulation symbols are mapped to the L layers and transmitted by using the L layers. The output bit sequences are generated by reading out entries of the interleaver matrix, column by column.