Invention Grant
US09545381B2 Process for drying of BIBW2992, of its salts and of solid pharmaceutical formulations comprising this active ingredient
有权
BIBW2992及其盐和包含该活性成分的固体药物制剂的干燥方法
- Patent Title: Process for drying of BIBW2992, of its salts and of solid pharmaceutical formulations comprising this active ingredient
- Patent Title (中): BIBW2992及其盐和包含该活性成分的固体药物制剂的干燥方法
-
Application No.: US13378379Application Date: 2010-07-05
-
Publication No.: US09545381B2Publication Date: 2017-01-17
- Inventor: Albert Barta
- Applicant: Albert Barta
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Edward S. Lazer
- Priority: EP09164659 20090706; EP10154562 20100224
- International Application: PCT/EP2010/059546 WO 20100705
- International Announcement: WO2011/003853 WO 20110113
- Main IPC: A61K9/28
- IPC: A61K9/28 ; A61K9/16 ; A61K9/20 ; C07C57/145
Abstract:
The present invention relates to a drying process of BIBW 2992 or the salts thereof, preferably the dimaleate salt, as well as of solid pharmaceutical formulations comprising BIBW2992 or a salt thereof, and to pharmaceutical compositions comprising BIBW 2992 or a salt thereof as the active product ingredient, characterized by a water activity of the formulation of not more than 0.20 or a water content (Karl-Fischer) of not more than 4.2%.
Public/Granted literature
Information query
