Invention Grant
US09546161B2 Synthesis of UDP-glucose: N-acylsphingosine glucosyl transferase inhibitors
有权
UDP-葡萄糖的合成：N-酰基鞘氨醇葡糖基转移酶抑制剂
- Patent Title: Synthesis of UDP-glucose: N-acylsphingosine glucosyl transferase inhibitors
- Patent Title (中): UDP-葡萄糖的合成：N-酰基鞘氨醇葡糖基转移酶抑制剂
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Application No.: US14315453Application Date: 2014-06-26
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Publication No.: US09546161B2Publication Date: 2017-01-17
- Inventor: Bradford H. Hirth , Craig Siegel
- Applicant: Genzyme Corporation
- Applicant Address: US MA Cambridge
- Assignee: Genzyme Corporation
- Current Assignee: Genzyme Corporation
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- Main IPC: C07D405/06
- IPC: C07D405/06 ; C07D405/10 ; C07D295/185 ; C07D319/18 ; C07D498/04 ; A61K31/4025
Abstract:
Disclosed is a novel enantiomeric synthesis ceramide-like inhibitors of UDP-glucose: N-acylsphingosine glucosyltransferase. Also disclosed are novel intermediates formed during the synthesis.
Public/Granted literature
- US20150148534A1 SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYL TRANSFERASE INHIBITORS Public/Granted day:2015-05-28
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