Invention Grant
- Patent Title: ERK inhibitors
- Patent Title (中): ERK抑制剂
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Application No.: US15103893Application Date: 2014-12-12
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Publication No.: US09546168B2Publication Date: 2017-01-17
- Inventor: Kathryn Lipford , Danielle Falcone , David L. Sloman , David J. Witter
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Catherine D. Fitch; Richard S. Parr
- International Application: PCT/US2014/069873 WO 20141212
- International Announcement: WO2015/094929 WO 20150625
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/437 ; A61K31/444 ; A61K45/06

Abstract:
Disclosed are the ERK inhibitors of formula (1.0) and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1.0). This invention provides compounds that are ERK inhibitors (i.e., ERK2 inhibitors). This invention also provides a pharmaceutical composition comprising an effective amount of at least one (e.g., 1) compound of formula (1.0) and a pharmaceutically acceptable carrier.
Public/Granted literature
- US20160311819A1 ERK INHIBITORS Public/Granted day:2016-10-27
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