Invention Grant
- Patent Title: MUC-1 cytoplasmic domain peptides as inhibitors of cancer
- Patent Title (中): MUC-1细胞质结构域肽作为癌症的抑制剂
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Application No.: US14620349Application Date: 2015-02-12
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Publication No.: US09546201B2Publication Date: 2017-01-17
- Inventor: Donald W. Kufe , Surender Kharbanda
- Applicant: DANA-FARBER CANCER INSTITUTE, INC. , GENUS ONCOLOGY, LLC
- Applicant Address: US MA Boston US IL Chicago
- Assignee: Dana-Farber Cancer Institute, Inc.,Genus Oncology, LLC
- Current Assignee: Dana-Farber Cancer Institute, Inc.,Genus Oncology, LLC
- Current Assignee Address: US MA Boston US IL Chicago
- Agency: Parker Highlander PLLC
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K7/06 ; C07K14/47 ; A61K38/17
Abstract:
Peptides from the Mucin 1 (MUC1) cytoplasmic domain and methods of use therefor are described. These peptides can inhibit MUC1 oligomerization, thereby preventing tumor cell growth, inducing tumor cell apoptosis and necrosis of tumor tissue in vivo.
Public/Granted literature
- US20150152152A1 MUC-1 CYTOPLASMIC DOMAIN PEPTIDES AS INHIBITORS OF CANCER Public/Granted day:2015-06-04
Information query
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