Invention Grant
US09546221B2 Fusion protein having transcription factor transactivation-regulating domain and protein transduction domain, and transcription factor function inhibitor comprising the same
有权
具有转录因子反式激活调节结构域和蛋白质转导结构域的融合蛋白，以及包含其的转录因子功能抑制剂
- Patent Title: Fusion protein having transcription factor transactivation-regulating domain and protein transduction domain, and transcription factor function inhibitor comprising the same
- Patent Title (中): 具有转录因子反式激活调节结构域和蛋白质转导结构域的融合蛋白，以及包含其的转录因子功能抑制剂
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Application No.: US13818062Application Date: 2011-08-19
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Publication No.: US09546221B2Publication Date: 2017-01-17
- Inventor: San-Kyou Lee , Tae Yoon Park , Ye Kyung Seong , Jen Young Cho , Jong Hyun Park , Sang Hwa Yang
- Applicant: San-Kyou Lee , Tae Yoon Park , Ye Kyung Seong , Jen Young Cho , Jong Hyun Park , Sang Hwa Yang
- Applicant Address: KR Seoul
- Assignee: Sang-Kyou Lee
- Current Assignee: Sang-Kyou Lee
- Current Assignee Address: KR Seoul
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Kongsik Kim; Richard B. Emmons
- Priority: KR10-2010-0080864 20100820; KR10-2010-0126455 20101210
- International Application: PCT/KR2011/006158 WO 20110819
- International Announcement: WO2012/023838 WO 20120223
- Main IPC: C07K19/00
- IPC: C07K19/00 ; C07K14/47 ; C12N15/62
Abstract:
This invention relates to a fusion protein comprising the TMD of the transcription factor and PTD, an inhibitor for transcription factor function comprising the same, and a method for producing the same. Various diseases associated with malfunctions or defects of the transcription factor are effectively treated using the fusion protein according to the present invention.
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