Invention Grant
- Patent Title: Nanopore sequencing using n-mers
- Patent Title (中): 使用n-mers进行纳孔测序
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Application No.: US14026906Application Date: 2013-09-13
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Publication No.: US09546400B2Publication Date: 2017-01-17
- Inventor: Stephen Turner , Benjamin Flusberg
- Applicant: Pacific Biosciences of California, Inc.
- Applicant Address: US CA Menlo Park
- Assignee: Pacific Biosciences of California, Inc.
- Current Assignee: Pacific Biosciences of California, Inc.
- Current Assignee Address: US CA Menlo Park
- Agent Robert H. Reamey
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N27/447 ; G01N33/487
Abstract:
The invention relates to devices and methods for nanopore sequencing. The invention provides for using the signals from n-mers to provide sequence information, for example where the system has less than single base resolution. The invention includes arrays of nanopores having incorporated electronic circuits, for example, in CMOS. In some cases, the arrays of nanopores comprise resistive openings for isolating the electronic signals for improved sequencing. Methods for controlling translocation of through the nanopore are disclosed.
Public/Granted literature
- US20140061048A1 NANOPORE SEQUENCING USING N-MERS Public/Granted day:2014-03-06
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