Invention Grant
- Patent Title: TNF -α modulating benzimidazoles
- Patent Title (中): TNF-α调节苯并咪唑
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Application No.: US14406848Application Date: 2013-06-11
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Publication No.: US09550737B2Publication Date: 2017-01-24
- Inventor: Daniel Christopher Brookings , Mark Daniel Calmiano , Ellen Olivia Gallimore , Helen Tracey Horsley , Martin Clive Hutchings , James Andrew Johnson , Boris Kroeplien , Fabien Claude Lecomte , Martin Alexander Lowe , Timothy John Norman , John Robert Porter , Joanna Rachel Quincey , James Thomas Reuberson , Matthew Duncan Selby , Michael Alan Shaw , Zhaoning Zhu , Anne Marie Foley
- Applicant: UCB Biopharma SPRL
- Applicant Address: BE Brussels
- Assignee: UCB Biopharma SPRL
- Current Assignee: UCB Biopharma SPRL
- Current Assignee Address: BE Brussels
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: GB1210233.1 20120611; GB1221983.8 20121206
- International Application: PCT/EP2013/062062 WO 20130611
- International Announcement: WO2013/186229 WO 20131219
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D401/14 ; C07D403/04 ; C07D491/107 ; C07D235/12 ; A61K31/4184 ; A61K31/4192 ; A61K31/4439 ; A61K31/444 ; A61K31/454 ; A61K31/4709 ; A61K31/4725 ; A61K31/506 ; A61K31/5377 ; A61K31/541 ; A61K31/551 ; C07D405/06
Abstract:
A series of benzimidazole derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
Public/Granted literature
- US20150152065A1 TNF -Alpha Modulating Benzimidazoles Public/Granted day:2015-06-04
Information query
