Invention Grant
- Patent Title: Heterocyclic ring and carbocyclic derivative
- Patent Title (中): 杂环和碳环衍生物
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Application No.: US14377331Application Date: 2013-02-08
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Publication No.: US09550763B2Publication Date: 2017-01-24
- Inventor: Hiroyuki Kai , Satoru Tanaka , Yoshiharu Hiramatsu , Azusa Nozu , Ken'ichioh Nakamura
- Applicant: Shionogi & Co., Ltd.
- Applicant Address: JP Osaka
- Assignee: SHIONOGI & CO., LTD.
- Current Assignee: SHIONOGI & CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: JP2012-025726 20120209; JP2012-148613 20120702
- International Application: PCT/JP2013/052991 WO 20130208
- International Announcement: WO2013/118855 WO 20130815
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D417/14 ; C07D405/14 ; C07D401/12 ; C07D405/12 ; C07D239/54 ; C07D417/12 ; C07D239/545 ; C07D401/14 ; C07D403/12 ; C07D413/12 ; C07D413/14

Abstract:
The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect, e.g. a compound of Formula (I): wherein R2 is a hydrogen atom or the like; ring A is five- to seven-cycloalkane or the like; C is a carbon atom; Q1 and Q2 are carbon atoms or the like; R9a and R9b are carbon atoms or the like; R6 is cycloalkyl or the like; R7 is a group represented by the formula: wherein ring D is benzene or the like; carbon atom a and b are carbon atoms; ring B is an aromatic carbocyclic ring or the like; s and s′ are 0 or the like; R9 and R9′ are halogen or the like, or the like, or its pharmaceutically acceptable salt.
Public/Granted literature
- US20160024072A1 Heterocyclic Ring and Carbocyclic Derivative Public/Granted day:2016-01-28
Information query
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