Invention Grant
- Patent Title: Pyrrolopyrrolone derivatives and their use as BET inhibitors
- Patent Title (中): 吡咯并吡咯啉衍生物及其作为BET抑制剂的用途
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Application No.: US15037116Application Date: 2014-11-20
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Publication No.: US09550796B2Publication Date: 2017-01-24
- Inventor: Heinrich Rueger , Jutta Blank , Vincent Bordas , Simona Cotesta , Guido Bold , Vito Guagnano , Andrea Vaupel
- Applicant: Heinrich Rueger , Jutta Blank , Vincent Bordas , Simona Cotesta , Guido Bold , Vito Guagnano , Andrea Vaupel
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agent Qian Zhang
- Priority: EP13193825 20131121
- International Application: PCT/IB2014/066199 WO 20141120
- International Announcement: WO2015/075665 WO 20150528
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/407 ; A61K31/44 ; A61K31/5377 ; A61K31/506 ; A61K31/41 ; A61K31/4439 ; A61K45/06 ; C07D519/00 ; A61K31/437 ; A61K31/444 ; A61K31/4192 ; A61K31/513 ; A61K31/5025
Abstract:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Public/Granted literature
- US20160280719A1 PYRROLOPYRROLONE DERIVATIVES AND THEIR USE AS BET INHIBITORS Public/Granted day:2016-09-29
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