Invention Grant
- Patent Title: Regulation of epigenetic control of gene expression
- Patent Title (中): 调控基因表达的表观遗传控制
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Application No.: US11721326Application Date: 2005-12-12
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Publication No.: US09550990B2Publication Date: 2017-01-24
- Inventor: Richard H. Griffey , Timothy Vickers , Ranjan Perera
- Applicant: Richard H. Griffey , Timothy Vickers , Ranjan Perera
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Baker & Hostetler LLP
- International Application: PCT/US2005/045063 WO 20051212
- International Announcement: WO2006/063356 WO 20060615
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113
Abstract:
Methods are provided for the identification of compounds that selectively modulate epigenetic changes in gene expression. Compounds, compositions, kits or assays devices, and methods are provided for modulating the expression, endogenous levels or the function of small non-coding RNAs cognate to or transcribed by heterochromatic regions subject to epigenetic regulation (i.e., promoters, enhancers, centromeres, telomeres, origins of DNA replication, imprinted loci, or loci marked by dosage-compensation), and for modulating the formation or function of heterochromatin in cells, tissues or animals.
Public/Granted literature
- US20090298910A1 REGULATION OF EPIGENETIC CONTROL OF GENE EXPRESSION Public/Granted day:2009-12-03
Information query
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