Invention Grant
- Patent Title: Recombinant host cells comprising phosphoketolases
- Patent Title (中): 包含磷酸酮醇酶的重组宿主细胞
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Application No.: US14335734Application Date: 2014-07-18
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Publication No.: US09550999B2Publication Date: 2017-01-24
- Inventor: Michael Dauner , Lori Ann Maggio-Hall , Jean-Francois Tomb
- Applicant: BUTAMAX ADVANCED BIOFUELS LLC
- Applicant Address: US DE Wilmington
- Assignee: Butamax Advanced Biofuels LLC
- Current Assignee: Butamax Advanced Biofuels LLC
- Current Assignee Address: US DE Wilmington
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12N1/00 ; C12N9/00 ; C12N15/00 ; C12P7/16 ; C07H21/04 ; C12N15/81 ; C12N9/02 ; C12N9/10 ; C12N9/88 ; C12N15/52 ; C12N15/74 ; C12P7/18 ; C12P7/26 ; C12P7/46 ; C12P7/56 ; C12P13/06 ; C12P13/08
Abstract:
The present invention is related to recombinant host cells comprising: (i) at least one deletion, mutation, and/or substitution in an endogenous gene encoding a polypeptide that converts pyruvate to acetaldehyde, acetyl-phosphate, or acetyl-CoA; and (ii) a heterologous polynucleotide encoding a polypeptide having phosphoketolase activity. The present invention is also related to recombinant host cells further comprising (iii) a heterologous polynucleotide encoding a polypeptide having phosphotransacetylase activity.
Public/Granted literature
- US20140349349A1 RECOMBINANT HOST CELLS COMPRISING PHOSPHOKETOLASES Public/Granted day:2014-11-27
Information query
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