Invention Grant
US09551033B2 Gene expression markers of tumor resistance to HER2 inhibitor treatment
有权
肿瘤抗HER2抑制剂治疗的基因表达标志物
- Patent Title: Gene expression markers of tumor resistance to HER2 inhibitor treatment
- Patent Title (中): 肿瘤抗HER2抑制剂治疗的基因表达标志物
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Application No.: US12806419Application Date: 2010-08-12
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Publication No.: US09551033B2Publication Date: 2017-01-24
- Inventor: Si Tuen Lee-Hoeflich , Howard Stern
- Applicant: Si Tuen Lee-Hoeflich , Howard Stern
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Arnold & Porter LLP
- Agent Diane Marschang; Ginger R. Dreger
- Main IPC: A61K39/395
- IPC: A61K39/395 ; G01N33/574 ; C12Q1/68

Abstract:
The present invention concerns markers of resistance of HER2 expressing tumors to treatment with HER2 inhibitors, such as HER2 antibodies, including trastuzumab.
Public/Granted literature
- US20110151454A1 Gene expression markers of tumor resistance to HER2 inhibitor treatment Public/Granted day:2011-06-23
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