Systems and methods may be provided to support memory access by packet communication and/or direct memory access. In one aspect, a memory controller may be provided for a processing device containing a plurality of computing resources. The memory controller may comprise a first interface to be coupled to a router. The first interface may be configured to transmit and receive packets. Each packet may comprise a header that may contain a routable address and a packet opcode specifying an operation to be performed in accordance with a network protocol. The memory controller may further comprise a memory bus port coupled to a plurality of memory slots that are configured to receive memory banks to form a memory and a controller core coupled to the first interface. The controller core may be configured to decode a packet received at the first interface and perform an operation specified in the received packet.