A POS docking station for a mobile scanner gun system or mobile tablet (tablet) processes POS sales transactions. An upper housing assembly enclosure houses the “tablet” in a “cradle fashion” fitting snuggly around the “tablet”, providing stability and form fit integration. An electrical connector integrates the upper housing to a printed circuit board (PCB1) to the “tablet”. A base housing assembly includes a scanner trigger button, a base mounting plate, a primary printed circuit board (PCB2) with at least one USB, Ethernet, Serial port, scan switch interface and an external power supply port, and a tilting and rotational mechanism. PCB1 is connected to PCB2 through an interface cable connecting the POS docking station to the “tablet”. USB, Ethernet, Serial ports, scan switch interface and power supply within the base housing assembly are fully operable to the “tablet”, and can be connected to a variety of store systems POS peripheral devices.