In various embodiments, a surgical staple cartridge is provided. The staple cartridge comprises a cartridge housing, a knife, a first row of staple pockets, a second row of staple pockets, and a third row of staple pockets. The staple cartridge further comprises a plurality of first staples, a plurality of second staples, and a plurality of third staples. The staple cartridge further comprises, one, a first staple driver oriented to drive a first staple out of the staple pockets in the first row, a second staple out of the staple pockets in the second row, and a third staple out of the staple pockets in the third row and, two, a second staple driver oriented to drive a total of four staples out of the staple pockets in the first row, the second row and the third row of staple pockets.