Invention Grant
- Patent Title: Use of modified vasoactive intestinal peptides in the treatment of hypertension
- Patent Title (中): 使用改良的血管活性肠肽治疗高血压
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Application No.: US14124612Application Date: 2012-06-06
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Publication No.: US09561262B2Publication Date: 2017-02-07
- Inventor: Lynne M. Georgopoulos , Susan Arnold
- Applicant: Lynne M. Georgopoulos , Susan Arnold
- Applicant Address: US PA Malvern
- Assignee: PHASEBIO PHARMACEUTICALS, INC.
- Current Assignee: PHASEBIO PHARMACEUTICALS, INC.
- Current Assignee Address: US PA Malvern
- Agency: Cooley LLP
- International Application: PCT/US2012/041092 WO 20120606
- International Announcement: WO2012/170524 WO 20121213
- Main IPC: A61K38/39
- IPC: A61K38/39 ; A61K31/4418 ; A61K31/4045 ; A61K31/165 ; C07K14/575 ; C07K14/78 ; A61K38/22 ; A61K45/06 ; A61K31/403 ; A61K38/00
Abstract:
The present invention is based on the discovery that a VIP having a binding preference for VPAC2 can provide long-acting blood pressure control synergistically with concomitant anti-hypertensive therapies. Accordingly, methods and compositions useful for the treatment and/or amelioration of hypertension are provided.
Public/Granted literature
- US20150111829A1 USE OF MODIFIED VASOACTIVE INTESTINAL PEPTIDES IN THE TREATMENT OF HYPERTENSION Public/Granted day:2015-04-23
Information query
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