Invention Grant
- Patent Title: Carrier-linked treprostinil prodrugs
- Patent Title (中): 载体连接的曲前列腺素前药
-
Application No.: US14238437Application Date: 2012-08-10
-
Publication No.: US09561287B2Publication Date: 2017-02-07
- Inventor: Ulrich Hersel , Harald Rau , Torben Lessmann , Nicola Bisek , Guillaume Maitro , Kennett Sprogøe , Thomas Wegge , Oliver Keil , Joachim Zettler
- Applicant: Ulrich Hersel , Harald Rau , Torben Lessmann , Nicola Bisek , Guillaume Maitro , Kennett Sprogøe , Thomas Wegge , Oliver Keil , Joachim Zettler
- Applicant Address: DK Hellerup
- Assignee: Ascendis Pharma A/S
- Current Assignee: Ascendis Pharma A/S
- Current Assignee Address: DK Hellerup
- Agency: Frommer Lawrence & Haug LLP
- Priority: EP11177409 20110812; EP11195615 20111223; EP12165508 20120425
- International Application: PCT/EP2012/065745 WO 20120810
- International Announcement: WO2013/024052 WO 20130221
- Main IPC: A61K47/48
- IPC: A61K47/48
Abstract:
The present invention relates to prodrugs or a pharmaceutically acceptable salt thereof comprising a covalent treprostinil carrier conjugate as well as pharmaceutical composition comprising said compounds. The compounds may be used as medicaments, especially for diseases or disorders which can be treated by treprostinil, such as pulmonary arterial hypertension (PAH).
Public/Granted literature
- US20140296150A1 Carrier-Linked Treprostinil Prodrugs Public/Granted day:2014-10-02
Information query
