Invention Grant
- Patent Title: Hemostatic compositions and dressings for bleeding
- Patent Title (中): 止血组合物和出血敷料
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Application No.: US14344998Application Date: 2012-09-14
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Publication No.: US09561300B2Publication Date: 2017-02-07
- Inventor: Linda Eastwood , Harold Coons , James M. Sinclair , Matthew D. Bacchetta , Gopal Singh
- Applicant: Linda Eastwood , Harold Coons , James M. Sinclair , Matthew D. Bacchetta , Gopal Singh
- Applicant Address: US CA Beverly Hills US NY New York
- Assignee: YES, INC.,THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee: YES, INC.,THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee Address: US CA Beverly Hills US NY New York
- Agency: Choate, Hall & Stewart, LLP
- International Application: PCT/US2012/055518 WO 20120914
- International Announcement: WO2013/048787 WO 20130404
- Main IPC: A61L15/40
- IPC: A61L15/40 ; A61L15/38 ; A61L15/44 ; A61K31/722 ; A61K36/185 ; A61K36/28 ; A61K45/06 ; A61K38/48 ; A61K31/185 ; A61K33/06 ; A61L15/18 ; A61L15/22 ; A61K38/36 ; A61L15/28 ; A61L15/32

Abstract:
The present invention provides hemostatic compositions comprising components of the flowers of pharmaceutical chamomile (Chamomilla recutita), the leaves of dioecious nettle (Urtica dioica), kaolin, chitosan, fibrinogen and thrombin. Further inclusion of a biocompatible polymeric base, particularly an alignate, generates a composition with superior and broad spectrum hemostatic capabilities, including the ability to arrest arterial hemorrhage. The invention further provides methods of using the inventive compositions in to reduce or stop bleeding, as well as a variety of apparatuses useful in hemostatic contexts that incorporate the inventive compositions. In one particular embodiment, the invention provides hemostatic dressings in which a polymeric layer incorporating chamomile, nettle, kaolin, chitosan, fibrinogen and thrombin components is applied to a textile or fabric material, for example a non-woven viscose.
Public/Granted literature
- US20150283286A1 NOVEL HEMOSTATIC COMPOSITIONS AND DRESSINGS FOR BLEEDING Public/Granted day:2015-10-08
Information query
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