Invention Grant
- Patent Title: Process of asymmetric hydrogenation of ketals and acetals
- Patent Title (中): 缩酮和缩醛的不对称氢化方法
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Application No.: US14652562Application Date: 2013-12-18
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Publication No.: US09561989B2Publication Date: 2017-02-07
- Inventor: Werner Bonrath , Thomas Netscher , Jonathan Alan Medlock , Gerardus Karel Maria Verzijl , Andreas Hendrikus Maria De Vries
- Applicant: DSM IP ASSETS B.V.
- Applicant Address: NL Heerlen
- Assignee: DSM IP ASSETS B.V.
- Current Assignee: DSM IP ASSETS B.V.
- Current Assignee Address: NL Heerlen
- Agency: Nixon & Vanderhye P.C.
- Priority: EP12197861 20121218
- International Application: PCT/EP2013/077231 WO 20131218
- International Announcement: WO2014/096096 WO 20140626
- Main IPC: C07D507/02
- IPC: C07D507/02 ; C07B35/02 ; C07D317/12 ; C07C41/48 ; C07B53/00 ; C07D311/72 ; C07D319/06 ; B01J31/18 ; C07C41/56 ; C07C41/58
Abstract:
The present invention relates to a process of the asymmetric hydrogenation of a ketal of an unsaturated ketone or an acetal of an unsaturated aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex. This process yields chiral compounds in a very efficient way and is very advantageous in that the amount of iridium complex can be remarkably reduced.
Public/Granted literature
- US20160185683A1 PROCESS OF ASYMMETRIC HYDROGENATION OF KETALS AND ACETALS Public/Granted day:2016-06-30
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