Invention Grant
US09562018B2 Sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine, preparation thereof and use of the same
有权
N-（3-（4-（3-（二异丁基氨基）丙基）哌嗪-1-基）丙基）-1H-苯并[d]咪唑-2-胺的硫酸盐，其制备及其用途
![Sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine, preparation thereof and use of the same](/docs/US/2017-02-07/US09562018B2/abs.jpg.600x600.jpg)
- Patent Title: Sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine, preparation thereof and use of the same
- Patent Title (中): N-（3-（4-（3-（二异丁基氨基）丙基）哌嗪-1-基）丙基）-1H-苯并[d]咪唑-2-胺的硫酸盐，其制备及其用途
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Application No.: US14655642Application Date: 2013-12-27
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Publication No.: US09562018B2Publication Date: 2017-02-07
- Inventor: Stéphane Burlet , Cécilia Estrella , Mathieu Barrier , Patricia Melnyk , Nicolas Sergeant , Luc Buee , Philippe Verwaerde
- Applicant: ALZPROTECT , UNIVERSITE DE LILLE 2 DROIT ET SANTE , INSERM (Institut National de la Santé et de la Recherche Médicale)
- Applicant Address: FR Loos
- Assignee: Alzprotect
- Current Assignee: Alzprotect
- Current Assignee Address: FR Loos
- Agency: McDonnell Boehnen Hulbert & Berghoff
- Priority: EP12306690 20121227
- International Application: PCT/EP2013/078068 WO 20131227
- International Announcement: WO2014/102339 WO 20140703
- Main IPC: C07D235/30
- IPC: C07D235/30 ; A61K31/496
![Sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine, preparation thereof and use of the same](/abs-image/US/2017/02/07/US09562018B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine and pharmaceutically acceptable solvates thereof, preparation thereof, pharmaceutical compositions containing them and use of the same in the treatment and/or prevention of neurodegenerative diseases.
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