Invention Grant
- Patent Title: Dihydroxy aromatic heterocyclic compound
- Patent Title (中): 二羟基芳香杂环化合物
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Application No.: US14885037Application Date: 2015-10-16
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Publication No.: US09562020B2Publication Date: 2017-02-07
- Inventor: Takeshi Hondo , Keita Nakanishi , Tatsuya Niimi , Masaichi Warizaya , Ichiji Namatame , Katsuya Harada
- Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP.
- Priority: JP2011-250143 20111115
- Main IPC: C07D253/06
- IPC: C07D253/06 ; A61K31/53 ; C07D237/16 ; C07D403/12 ; C07D401/14 ; C07D405/14 ; A61K31/4412 ; A61K31/4418 ; A61K31/4427 ; A61K31/443 ; A61K31/4433 ; A61K31/4439 ; A61K31/444 ; A61K31/496 ; A61K31/50 ; A61K31/501 ; A61K31/5377 ; A61K31/551 ; C07D401/06 ; C07D401/12 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07D417/14 ; C07D471/04 ; C07D471/10 ; C07D487/04 ; C07D213/69 ; C07D403/06 ; C07D405/06 ; C07D409/06 ; C07D413/06 ; C07D413/10 ; C07D417/06 ; C07D253/07 ; C07D491/056
Abstract:
Provided is a compound having a D-amino acid oxidase (DAAO) inhibitory action, and useful as for example, a prophylaxis and/or therapeutic agent for schizophrenia or neuropathic pain. The present inventors have studied a compound that inhibits DAAO, and confirm that a dihydroxy aromatic heterocyclic compound has a DAAO inhibitory action, and completed the present invention. That is, the dihydroxy aromatic heterocyclic compound of the present invention has a good DAAO inhibitory action, and can be used as a prophylaxis and/or therapeutic agent for, for example, schizophrenia or neuropathic pain.
Public/Granted literature
- US20160039771A1 DIHYDROXY AROMATIC HETEROCYCLIC COMPOUND Public/Granted day:2016-02-11
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