Invention Grant
US09562025B2 Compounds with (1E, 6E)-1,7-Bis-(3,4-dimethoxyphenyl)-4-4-distributed-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof
有权
化合物与（1E，6E）-1,7-双 - （3,4-二甲氧基苯基）-4-4-分布 - 七-1,6-二烯-3,5-二酮结构支架，它们的生物活性和用途 其中
- Patent Title: Compounds with (1E, 6E)-1,7-Bis-(3,4-dimethoxyphenyl)-4-4-distributed-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof
- Patent Title (中): 化合物与（1E，6E）-1,7-双 - （3,4-二甲氧基苯基）-4-4-分布 - 七-1,6-二烯-3,5-二酮结构支架，它们的生物活性和用途 其中
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Application No.: US15044685Application Date: 2016-02-16
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Publication No.: US09562025B2Publication Date: 2017-02-07
- Inventor: Charles Shih , Qian Shi , Hui-Kang Wang
- Applicant: Allianz Pharmascience Ltd.
- Applicant Address: TW Taipei
- Assignee: Allianz Pharmascience Ltd.
- Current Assignee: Allianz Pharmascience Ltd.
- Current Assignee Address: TW Taipei
- Agency: Cesari and McKenna LLP
- Main IPC: C07C49/255
- IPC: C07C49/255 ; C07C69/618 ; C07D295/192 ; A61K31/00 ; C07D295/16 ; C07C309/65 ; C07D277/46 ; C07C235/78 ; A61K31/12 ; A61K31/165 ; A61K31/426 ; A61K31/5375 ; A61K31/255 ; C07C59/90 ; C07C69/738 ; C07C235/74 ; C07D277/44
Abstract:
The present invention relates to compounds having at least one (substituted phenyl)-propenal moiety. The compounds are useful in treating a subject suffering from an androgen receptor-associated medical condition, e.g., inflammation, acne, alopecia, hirsutism, wound, Spinal and Bulbar Muscular Atrophy (SBMA, Kennedy's Disease), unwanted immune response, immune disorder, or cancer.
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