Invention Grant
US09562035B2 Benzamide derivative useful as FASN inhibitors for the treatment of cancer
有权
苯甲酰胺衍生物可用作治疗癌症的FASN抑制剂
- Patent Title: Benzamide derivative useful as FASN inhibitors for the treatment of cancer
- Patent Title (中): 苯甲酰胺衍生物可用作治疗癌症的FASN抑制剂
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Application No.: US14550349Application Date: 2014-11-21
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Publication No.: US09562035B2Publication Date: 2017-02-07
- Inventor: Peter J Connolly , Tianbao Lu
- Applicant: Janssen Pharmaceutica NV
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D487/04 ; C07D417/14 ; C07D413/14 ; C07D401/10 ; C07D409/14 ; C07D405/14 ; A61K31/5377 ; A61K31/4725 ; A61K31/496 ; A61K31/506 ; A61K31/4709 ; C07D401/12 ; C07D403/10 ; C07D471/04 ; A61K31/437 ; A61K31/454 ; A61K31/4545
Abstract:
The present invention is directed to benzamide derivatives, pharmaceutical compositions containing them, and their use as FASN inhibitors, in for example, the treatment of cancer, obesity related disorders, liver related disorders and viral infections. Such compounds are represented by formula (I) as follows: wherein R1, R2, R3, R4, R5, m, n, are defined herein.
Public/Granted literature
- US20160009688A1 BENZAMIDE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER Public/Granted day:2016-01-14
Information query
