Invention Grant
US09562045B2 Process for preparation of indolizine based derivatives as potential phosphodiestrase 3 (PDE3) inhibitors
有权
制备中和衍生物作为潜在磷酸二酯酶3（PDE3）抑制剂的方法
- Patent Title: Process for preparation of indolizine based derivatives as potential phosphodiestrase 3 (PDE3) inhibitors
- Patent Title (中): 制备中和衍生物作为潜在磷酸二酯酶3（PDE3）抑制剂的方法
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Application No.: US15000738Application Date: 2016-01-19
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Publication No.: US09562045B2Publication Date: 2017-02-07
- Inventor: Budde Mahendar , Saidulu Mattapally , Mettu Ravinder , Sanjay Kumar Banerjee , Vaidya Jayathirtha Rao
- Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
- Applicant Address: IN New Delhi
- Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
- Current Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
- Current Assignee Address: IN New Delhi
- Agency: Abelman, Frayne & Schwab
- Priority: IN0287-DEL-2013 20130201
- Main IPC: C07D221/02
- IPC: C07D221/02 ; C07D471/04
Abstract:
The present invention provides compounds of general formula 1 useful as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula 1 can be employed as therapeutics in human and veterinary medicine, where they can be used, for example, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases.
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