Invention Grant
- Patent Title: Anticancer maytansinoids with two fused macrocyclic rings
- Patent Title (中): 具有两个稠合大环的抗癌美登木素生物碱
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Application No.: US15100985Application Date: 2014-12-02
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Publication No.: US09562059B2Publication Date: 2017-02-07
- Inventor: Hongjie Zhang , Djaja D. Soejarto , Harry H. S. Fong
- Applicant: Hong Kong Baptist University , The Board of Trustees of the University of Illinois
- Applicant Address: CN Hong Kong US IL Urbana
- Assignee: Hong Kong Baptist University,The Board of Trustees of the University of Illinois
- Current Assignee: Hong Kong Baptist University,The Board of Trustees of the University of Illinois
- Current Assignee Address: CN Hong Kong US IL Urbana
- Agent Daniel R. Collopy
- International Application: PCT/CN2014/092834 WO 20141202
- International Announcement: WO2015/081857 WO 20150611
- Main IPC: C07D498/22
- IPC: C07D498/22
Abstract:
This invention provides maytansinoids having improved tumor inhibition activity. In particular, the present invention provides a method of treatment of cancer, in particular colon cancer, using maytansinoid compounds having two fused macrocyclic rings.
Public/Granted literature
- US20160289244A1 ANTICANCER MAYTANSINOIDS WITH TWO FUSED MACROCYCLIC RINGS Public/Granted day:2016-10-06
Information query
