Invention Grant
US09562060B2 Heterocyclic pyridone compound, and intermediate, preparation method and use thereof
有权
杂环吡啶酮化合物及其中间体，其制备方法和用途
- Patent Title: Heterocyclic pyridone compound, and intermediate, preparation method and use thereof
- Patent Title (中): 杂环吡啶酮化合物及其中间体，其制备方法和用途
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Application No.: US14124628Application Date: 2012-05-28
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Publication No.: US09562060B2Publication Date: 2017-02-07
- Inventor: Jianjun Cheng , Jihong Qin , Bin Ye
- Applicant: Jianjun Cheng , Jihong Qin , Bin Ye
- Applicant Address: CN Shanghai
- Assignee: SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO., LTD
- Current Assignee: SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO., LTD
- Current Assignee Address: CN Shanghai
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Priority: CN201110154250 20110609
- International Application: PCT/CN2012/000741 WO 20120528
- International Announcement: WO2012/167600 WO 20121213
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; C07D513/04 ; C07D471/04 ; C07D498/04
Abstract:
The present invention relates to a heterocyclic pyridone compound represented by General Formula (I), where the heterocyclic pyridone compound is used as a tyrosine kinase inhibitor, and particularly a c-Met inhibitor. The present invention also relates to intermediates for preparing heterocyclic pyridone compound and a preparation method. The present invention further relates to a pharmaceutical composition containing the heterocyclic pyridone compound as an active ingredient, and a use of the pharmaceutical composition in treatment of diseases associated with tyrosine kinase c-Met, especially cancer associated with c-Met, as a medicament.
Public/Granted literature
- US20140206679A1 HETEROCYCLIC PYRIDONE COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF Public/Granted day:2014-07-24
Information query
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