Invention Grant
- Patent Title: Induction of tumor immunity by variants of folate binding protein
- Patent Title (中): 通过叶酸结合蛋白的变体诱导肿瘤免疫
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Application No.: US14339797Application Date: 2014-07-24
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Publication No.: US09562070B2Publication Date: 2017-02-07
- Inventor: Constantin G. Ioannides , George E. Peoples
- Applicant: Board of Regents, The University of Texas System , The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- Applicant Address: US TX Austin US MD Bethesda
- Assignee: Board of Regents, The University of Texas System,The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- Current Assignee: Board of Regents, The University of Texas System,The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- Current Assignee Address: US TX Austin US MD Bethesda
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Cynthia L. Kanik
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K7/06 ; C07K14/47 ; A61K39/17 ; A61K39/00
Abstract:
The present invention is directed to variants of antigens comprising folate binding protein epitopes as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by anergy, as in unresponsiveness.
Public/Granted literature
- US20150175658A1 INDUCTION OF TUMOR IMMUNITY BY VARIANTS OF FOLATE BINDING PROTEIN Public/Granted day:2015-06-25
Information query
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