Invention Grant
- Patent Title: Labeled alginate conjugates for molecular imaging applications
- Patent Title (中): 用于分子成像应用的标记的藻酸盐缀合物
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Application No.: US14989041Application Date: 2016-01-06
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Publication No.: US09562113B2Publication Date: 2017-02-07
- Inventor: Fuqiang Ruan , Thomas L. Deckwerth , Martin D. Meglasson
- Applicant: Bellerophon BCM LLC
- Applicant Address: US NJ Warren
- Assignee: Bellerophon BCM LLC
- Current Assignee: Bellerophon BCM LLC
- Current Assignee Address: US NJ Warren
- Agency: Servilla Whitney LLC
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14 ; C08B37/00 ; A61K51/06 ; C07B59/00 ; C07D255/02 ; C07F1/08 ; C07F5/00 ; A61K49/04 ; A61K51/04
Abstract:
Described are bifunctional NOTA-based derivatives capable of conjugating with alginate and with metal ions, as well as NOTA-alginate conjugates which can be labeled with stable or radioactive metal ions. Also described are conjugation methods of the bifunctional NOTA-based linker with alginate, and methods of using radiometal-labeled NOTA-alginate conjugates or other radio-labeled alginate conjugates as imaging reagents.
Public/Granted literature
- US20160115252A1 Labeled Alginate Conjugates For Molecular Imaging Applications Public/Granted day:2016-04-28
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