Invention Grant
- Patent Title: Methods of enhancing translocation of charged analytes through transmembrane protein pores
- Patent Title (中): 通过跨膜蛋白质孔增强带电分析物易位的方法
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Application No.: US14334285Application Date: 2014-07-17
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Publication No.: US09562887B2Publication Date: 2017-02-07
- Inventor: Giovanni Maglia , John Hagan Pryce Bayley
- Applicant: Isis Innovation Limited
- Applicant Address: GB Oxford
- Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
- Current Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
- Current Assignee Address: GB Oxford
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Adam J. Gastonguay
- Priority: GB0820927.2 20081114
- Main IPC: G01N33/487
- IPC: G01N33/487 ; C07K14/245 ; C12Q1/68 ; G01N33/68 ; G01N27/447

Abstract:
The invention relates to enhancing translocation of a charged analyte through a transmembrane protein pore. Translocation is enhanced by increasing the net opposing charge of the barrel or channel and/or entrance of the pore. The invention also relates to pores enhanced in accordance with the invention.
Public/Granted literature
- US20150008126A1 METHODS OF ENHANCING TRANSLOCATION OF CHARGED ANALYTES THROUGH TRANSMEMBRANE PROTEIN PORES Public/Granted day:2015-01-08
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