Invention Grant
US09562912B2 Method of identifying abnormal cells by expression levels of ETFB
有权
通过ETFB表达水平鉴定异常细胞的方法
- Patent Title: Method of identifying abnormal cells by expression levels of ETFB
- Patent Title (中): 通过ETFB表达水平鉴定异常细胞的方法
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Application No.: US14342774Application Date: 2011-12-27
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Publication No.: US09562912B2Publication Date: 2017-02-07
- Inventor: Shigenari Hirokawa , Hiroyuki Kitajima , Tomomasa Shimanuki
- Applicant: Shigenari Hirokawa , Hiroyuki Kitajima , Tomomasa Shimanuki
- Applicant Address: JP Tokyo
- Assignee: POLA PHARMA INC.
- Current Assignee: POLA PHARMA INC.
- Current Assignee Address: JP Tokyo
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: JP2011-206582 20110905
- International Application: PCT/JP2011/080247 WO 20111227
- International Announcement: WO2013/035209 WO 20130314
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/68 ; G01N33/50 ; C12N15/113

Abstract:
Provided is a method for identifying and suppressing abnormal growth of fibroblasts at an early stage. Provided is a method for identifying the growth state of fibroblasts using as an index the level of expression of ETFB (electron transfer flavoprotein beta subunit), comprising: judging, in cases where the level of expression of ETFB is high, that there is a high probability that fibroblasts are abnormally growing; and judging, in cases where the level of expression of ETFB is low, that there is a high probability that fibroblasts are normally growing. Further, by inhibition of ETFB, abnormal growth of fibroblasts can be suppressed.
Public/Granted literature
- US20140235491A1 METHOD OF APPLYING ETFB TO ABNORMAL PROLIFERATION OF CELL, AND ABNORMAL PROLIFERATION INHIBITOR Public/Granted day:2014-08-21
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